Construction of a host range-expanded hybrid baculovirus of BmNPV and AcNPV, and knockout of cysteinase gene for more efficient expression

@article{Wu2004ConstructionOA,
  title={Construction of a host range-expanded hybrid baculovirus of BmNPV and AcNPV, and knockout of cysteinase gene for more efficient expression},
  author={Xiao-feng Wu and Cuiping Cao and Yaxiang Xu and Xingmeng Lu},
  journal={Science in China Series C: Life Sciences},
  year={2004},
  volume={47},
  pages={406-415}
}
AcNPV (Autographa californica nuclear polyhedrosis virus) and BmNPV(Bombyx mori nuclear polyhedrosis virus) are two principal insectbaculovirus expression systems, each having different characteristics. AcNPV has a wider host range and can infect a series of cell lines thus making it suitable for cell suspension culture expression, but the small size of the… CONTINUE READING