Construction of a Quality of Life Questionnaire for slowly progressive neuromuscular disease

  title={Construction of a Quality of Life Questionnaire for slowly progressive neuromuscular disease},
  author={Antoine Dany and Coralie Barbe and Amandine Rapin and Christian R{\'e}veill{\`e}re and J B Hardouin and Isabella Morrone and Aurore Wolak-Thierry and Moustapha Dram{\'e} and Arnaud Calmus and Sabrina Sacconi and Guillaume Bassez and Vincent Tiffreau and Isabelle Richard and Benjamin Gallais and H{\'e}l{\'e}ne Prigent and Redha Taiar and Damien Jolly and Jean-Luc Novella and François Constant Boyer},
  journal={Quality of Life Research},
PurposeTo build a questionnaire to assess health-related quality of life (HRQL) in patients suffering from slowly progressive neuromuscular disease (NMD) using item response theory (IRT).MethodsA pool of 64 items and a validated questionnaire (WHOQOL-BREF) were administered to 159 patients recruited in eight NMD referral centers. Exploratory statistical analysis included methods derived from both IRT and classical test theory.ResultsWe constructed a questionnaire named QoL–NMD which is composed… 

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