Construction of Metal-Ion-Free G-quadruplex-Hemin DNAzyme and Its Application in S1 Nuclease Detection.

Abstract

In this work, a new kind of peroxidase-mimicking DNAzyme (G-quadruplex-hemin DNAzyme, G4-hemin) was constructed by using hemin-modified G-rich DNA (hemin-G-DNA). Experimental results demonstrated that the G-rich DNA can form a G-quadruplex structure by the inducement of terminally modified hemin, rendering the assembly of hemin and G-quadruplex structure… (More)
DOI: 10.1021/acsami.5b10165

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Cite this paper

@article{Wang2016ConstructionOM, title={Construction of Metal-Ion-Free G-quadruplex-Hemin DNAzyme and Its Application in S1 Nuclease Detection.}, author={Zhaoyin Wang and Jian Zhao and Jianchun Bao and Zhihui Dai}, journal={ACS applied materials & interfaces}, year={2016}, volume={8 1}, pages={827-33} }