Construction and properties of fusion proteins between human interferon-gamma and human tumour necrosis factors alpha and beta.

Abstract

A number of recombinant plasmids coding for fusion proteins between human interferon-gamma (IFN-gamma) and human tumour necrosis factor alpha (TNF alpha) or beta (TNF beta) were constructed by using site-directed mutagenesis and ligation of the respective genes. In these proteins the whole IFN-gamma sequence of the molecule is linked at the N terminus via a… (More)

Topics

Cite this paper

@article{Korobko1991ConstructionAP, title={Construction and properties of fusion proteins between human interferon-gamma and human tumour necrosis factors alpha and beta.}, author={Vyacheslav G. Korobko and Ilia V Davydov and Lyudmila N Shingarova and Sergey A. Filippov and Dmitry Esipov and V. Dobrynin}, journal={Biomedical science}, year={1991}, volume={2 6}, pages={634-40} }