Construction and functional analysis of an anti-human cervical carcinoma/anti-human CD3 single-chain bispecific antibody.

Abstract

The aim of the present study was to construct a single-chain bispecific antibody (scBsAb) against cervical carcinoma and to investigate its biological activities. The scBsAb was constructed using a genetic cloning technique and antigen binding activities were detected by ELISA. The iodogen method was used to analyze the pharmacokinetics. The Rosette… (More)
DOI: 10.3892/mmr.2016.5292

Topics

6 Figures and Tables

Cite this paper

@article{Wu2016ConstructionAF, title={Construction and functional analysis of an anti-human cervical carcinoma/anti-human CD3 single-chain bispecific antibody.}, author={Hong Wu and Li Yao and Lin Shih-Shen Chou and Jin-hua Yang and Yun-Xiu Zhang and Xiaoli Li and Bo-er Shan}, journal={Molecular medicine reports}, year={2016}, volume={14 1}, pages={804-10} }