Corpus ID: 85806254

Construction and deconstruction: The influence of lateral gene transfer on the evolution of the Tree of Life

  title={Construction and deconstruction: The influence of lateral gene transfer on the evolution of the Tree of Life},
  author={Maureen A O'Malley},
Efforts to construct the tree of life take their conceptual motivation from Charles Darwin’s theory of evolution. Until the advent of molecular biology, however, a universal tree of life was well beyond the scope of the data and methods of traditional organismal phylogeny. The rapid development of these methods and bodies of genetic sequence from the 1970s onwards resulted in major reclassifications of life and revived ambitions to represent all organismal lineages by one true tree of life… Expand
5 Citations
The tree of life: introduction to an evolutionary debate
The 'Tree of Life' is intended to represent the pattern of evolutionary processes that result in bifurcating species lineages. Often justified in reference to Darwin's discussions of trees, the TreeExpand
The tree of life: introduction to an evolutionary debate
This special issue examines scientific, historical and philosophical aspects of debates about the Tree of Life, with the aim of turning these criticisms towards a reconstruction of prokaryote phylogeny and even some aspects of the standard evolutionary understanding of eukaryotes. Expand
How stands the Tree of Life a century and a half after The Origin?
The original TOL hypothesis has failed but a new "statistical T OL hypothesis" is promising and the TOL heuristic usefully organizes data without positing fundamental evolutionary truth. Expand
Business models as models
Drawing on research undertaken in the history and philosophy of science, with particular reference to the extensive literature which discusses the use of models in biology and economics, we exploreExpand


The practice of classification and the theory of evolution, and what the demise of Charles Darwin's tree of life hypothesis means for both of them
  • W. Doolittle
  • Biology, Medicine
  • Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2009
It is argued that for Darwin the tree of life was a hypothesis, which lateral gene transfer in prokaryotes now shows to be false, and a more general and relaxed evolutionary theory is proposed. Expand
Horizontal gene transfer from extinct and extant lineages: biological innovation and the coral of life
Several distinct HGT events involving all three domains of life are discussed, illustrating the selective advantages that can be conveyed via HGT, and the utility of HGT in aiding phylogenetic reconstruction and in dating the relative sequence of speciation events. Expand
Ancient horizontal gene transfer
Comparative sequence analyses of genomes indicates that the universal tree of life might be at risk because of pervasive, ancient HGT, and considerable debate now ensues about the role of HGT in genome evolution. Expand
Darwinian evolution in the light of genomics
  • E. Koonin
  • Biology, Medicine
  • Nucleic acids research
  • 2009
Several universals of genome evolution were discovered including the invariant distributions of evolutionary rates among orthologous genes from diverse genomes and of paralogous gene family sizes, and the negative correlation between gene expression level and sequence evolution rate. Expand
Ancient horizontal gene transfer can benefit phylogenetic reconstruction.
The recent progress in phylogenetic application of ancient HGTs is discussed and two examples of transfer events to the ancestor of red algae and green plants that support a common origin of these two groups are described. Expand
The early evolution of cellular life.
  • J. Gogarten
  • Biology, Medicine
  • Trends in ecology & evolution
  • 1995
Advances in the study of origin of life are discussed in the following areas: the fossil recordsd; the 'retrodiction' of biochemical pathways; and contradictions between different molecular phylogenies. Expand
Genome beginnings: rooting the tree of life
A new root of life obtained through the analysis of indels, insertions and deletions, found within paralogous gene sets is introduced, implying that the last common ancestor was not hyperthermophilic, although moderate thermophily cannot be excluded. Expand
Prokaryotic evolution in light of gene transfer.
The role of recombination and HGT in giving phenotypic "coherence" to prokaryotic taxa at all levels of inclusiveness, the implications of these processes for the reconstruction and meaning of "phylogeny," and new views of proKaryotic adaptation and diversification based on gene acquisition and exchange are discussed. Expand
Uprooting the tree of life.
Uprooting the Tree of Life discusses the evolution on life on earth, including the theory known as the universal tree of life, as well as various conceptions of evolution, since Charles Darwin proposed it. Expand
Molecular evolution: Lateral gene transfer and other possibilities
Genome sequences have provided sound evidence that both endosymbiosis among eukaryotes, and LGT – among prokaryotes – are indeed real, although there is still much debate as to just how frequently either has occurred during evolution. Expand