Construction and characterization of an Actinobacillus pleuropneumoniae serotype 2 mutant lacking the Apx toxin secretion protein genes apxIIIB and apxIIID.

@article{Park2009ConstructionAC,
  title={Construction and characterization of an Actinobacillus pleuropneumoniae serotype 2 mutant lacking the Apx toxin secretion protein genes apxIIIB and apxIIID.},
  author={Changbo Park and Yooncheol Ha and Soohee Kim and Chanhee Chae and Doug-Young Ryu},
  journal={The Journal of veterinary medical science},
  year={2009},
  volume={71 10},
  pages={1317-23}
}
Apx toxins have been identified as important virulence factors of Actinobacillus pleuropneumoniae, the etiologic agent of porcine pleuropneumonia. In some A. pleuropneumoniae serotypes, Apx toxins are secreted by the cell membrane proteins encoded by apxIIIB and apxIIID genes. In an effort to develop a live vaccine strain against A. pleuropneumoniae, we… CONTINUE READING