Construction and characterization of an electrospun tubular scaffold for small-diameter tissue-engineered vascular grafts: a scaffold membrane approach.

@article{Hu2012ConstructionAC,
  title={Construction and characterization of an electrospun tubular scaffold for small-diameter tissue-engineered vascular grafts: a scaffold membrane approach.},
  author={Jin-Jia Hu and Wei-Chih Chao and Pei-Yuan Lee and Chih-Hao Huang},
  journal={Journal of the mechanical behavior of biomedical materials},
  year={2012},
  volume={13},
  pages={140-55}
}
Based on a postulate that the microstructure of a scaffold can influence that of the resulting tissue and hence its mechanical behavior, we fabricated a small-diameter tubular scaffold (∼3 mm inner diameter) that has a microstructure similar to the arterial media using a scaffold membrane approach. Scaffold membranes that contain randomly oriented, moderately aligned, or highly aligned fibers were fabricated by collecting electrospun poly([epsilon]-caprolactone) fibers on a grounded rotating… CONTINUE READING

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