Construction and characterization of E1-minus replication-defective adenovirus vectors that express E3 proteins from the E1 region.

@article{Tth2002ConstructionAC,
  title={Construction and characterization of E1-minus replication-defective adenovirus vectors that express E3 proteins from the E1 region.},
  author={K{\'a}roly T{\'o}th and Mohan Kuppuswamy and Konstantin Doronin and Oksana Doronina and Drew L. Lichtenstein and Ann E. Tollefson and William S. M. Wold},
  journal={Virology},
  year={2002},
  volume={301 1},
  pages={99-108}
}
Previous research has indicated that the adenovirus protein complex named RID, derived from the E3 transcription unit, functions to remove the receptors named Fas/Apo1/CD95 (Fas) and epidermal growth factor receptor (EGFR) from the surface of cells. (The RID complex is composed of the RIDalpha and RIDbeta polypeptides, previously named 10.4K and 14.5K… CONTINUE READING