Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire.


The ability to isolate antibodies against any antigen of interest has become increasingly important as antibodies have proved their utility both in antigen detection, quantification and as specific in vivo targeting agents. To this end, we have constructed a large antibody phage library in the single chain Fv (scFv) phagemid format based on the naive human… (More)