Constraints on intron evolution in the gene encoding the myosin alkali light chain in Drosophila.

@article{Leicht1995ConstraintsOI,
  title={Constraints on intron evolution in the gene encoding the myosin alkali light chain in Drosophila.},
  author={B G Leicht and Spencer V. Muse and Martin M. Hanczyc and Andrew G. Clark},
  journal={Genetics},
  year={1995},
  volume={139 1},
  pages={299-308}
}
Interspecific comparisons of intron sequences reveal conserved blocks of invariant nucleotides and several other departures from the strictly neutral model of molecular evolution. To distinguish the past action of evolutionary forces in introns known to have regulatory information, we examined nucleotide sequence variation at 991 sites in a random sample of 16 Drosophila melanogaster alleles of the gene encoding the myosin alkali light chain (Mlc1). The Mlc1 gene of D. melanogaster encodes two… CONTINUE READING
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