Constraint-induced movement therapy and rehabilitation exercises lessen motor deficits and volume of brain injury after striatal hemorrhagic stroke in rats.

@article{DeBow2003ConstraintinducedMT,
  title={Constraint-induced movement therapy and rehabilitation exercises lessen motor deficits and volume of brain injury after striatal hemorrhagic stroke in rats.},
  author={Suzanne B DeBow and M L Davies and Heather Clarke and Frederick Colbourne},
  journal={Stroke},
  year={2003},
  volume={34 4},
  pages={
          1021-6
        }
}
BACKGROUND AND PURPOSE Constraint-induced movement therapy (CIMT) promotes motor recovery after occlusive stroke in humans, but its efficacy after intracerebral hemorrhage (ICH) has not been investigated clinically or in the laboratory. In this study we tested whether CIMT and a rehabilitation exercise program would lessen motor deficits after ICH in rats. METHODS Rats were subjected to striatal ICH (via infusion of collagenase) or sham stroke. Seven days later, treatment began with CIMT (8 h… CONTINUE READING

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