Constraint and Adaptation in newt Toll-Like Receptor Genes

  title={Constraint and Adaptation in newt Toll-Like Receptor Genes},
  author={Wiesław Babik and Katarzyna Dudek and Anna Fijarczyk and Maciej Pabijan and Michał Tadeusz Stuglik and Rafał Szkotak and Piotr Zielinski},
  booktitle={Genome biology and evolution},
Acute die-offs of amphibian populations worldwide have been linked to the emergence of viral and fungal diseases. Inter and intraspecific immunogenetic differences may influence the outcome of infection. Toll-like receptors (TLRs) are an essential component of innate immunity and also prime acquired defenses. We report the first comprehensive assessment of TLR gene variation for urodele amphibians. The Lissotriton newt TLR repertoire includes representatives of 13 families and is… CONTINUE READING
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