Constraint Database Solutions to the Genome Map Assembly Problem

Abstract

Long DNA sequences have to be cut using restriction enzymes into small fragments whose lengths and/or nucleotide sequences can be analyzed by currently available technology. Cutting multiple copies of the same long DNA sequence using different restriction enzymes yields many fragments with overlaps that allow the fragments to be assembled into the order as… (More)
DOI: 10.1007/978-3-540-25954-1_6

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