Constitutive roles for inducible genes: evidence for the alteration in expression of the inducible hsp70 gene in Antarctic notothenioid fishes.

@article{Place2004ConstitutiveRF,
  title={Constitutive roles for inducible genes: evidence for the alteration in expression of the inducible hsp70 gene in Antarctic notothenioid fishes.},
  author={Sean P. Place and Mackenzie L. Zippay and Gretchen E. Hofmann},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2004},
  volume={287 2},
  pages={
          R429-36
        }
}
Previous research on the Antarctic notothenioid fish Trematomus bernacchii demonstrated the loss of the heat shock response (HSR), a classical cellular defense mechanism against thermal stress, characterized by the rapid synthesis of heat shock proteins (Hsps). In the current study, we examined potential mechanisms for the apparent loss of the HSR in Antarctic notothenioids and, in addition, compared expression patterns of two genes from the 70-kDa Hsp family (hsc71 and hsp70) in tissues from T… 
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Constitutive expression of a stress-inducible heat shock protein gene, hsp70, in phylogenetically distant Antarctic fish
TLDR
This study examined the extent of the loss of the heat-shock response characterized by the rapid synthesis of molecular chaperones in response to increasing pools of damaged proteins in Antarctic notothenioid fishes and indicated that the expression of hsc71 is similar in all species; however, the constitutive expression of the inducible hsp70 gene was also manifested in these species.
Characterization of Inducible HSP70 Genes in an Antarctic Yeast, Glaciozyma antarctica PI12, in Response to Thermal Stress
TLDR
Both analyzed HSP70s played important roles in the physiological adaptation of G. antarctica and proved that these psychrophilic chaperones can perform activities in a wide range of temperatures, such as at 37, 25, 15, and 4 °C.
Evolution of chaperome gene expression and regulatory elements in the antarctic notothenioid fishes.
TLDR
This study shows that evolution in chronic cold has led to both subtle and distinctive changes in the cellular apparatus for proteostasis and HSR, with functional consequences amenable to experimental evaluation.
Lack of an HSP70 heat shock response in two Antarctic marine invertebrates
TLDR
Members of the HSP70 gene family comprising the inducible (HSP70) genes and GRP78 (glucose-regulated protein 78 kDa) were identified in an Antarctic sea star and an Antarctic gammarid and the classical heat shock response is absent in both species.
Antarctic marine molluscs do have an HSP70 heat shock response
TLDR
This study shows that this is not the case for other Antarctic animals, with the two molluscs showing an inducible heat shock response, at a level probably set during their temperate evolutionary past.
The HSP70 heat shock response in the Antarctic fish Harpagifer antarcticus
TLDR
The results demonstrate the loss of the heat shock response in H. antarcticus, a basal member of the Notothenioidei, and the reorganisation of cellular protein mechanisms of species living in extreme environments is discussed.
Triggers of the HSP70 stress response: environmental responses and laboratory manipulation in an Antarctic marine invertebrate (Nacella concinna)
TLDR
A further series of experiments comprising both laboratory manipulation and environmental sampling of N. concinna provide intriguing clues not only to the complexity of HSP70 gene expression in response to environmental change but also insights into the stress response of a non-model species.
Regulation of heat shock genes in isolated hepatocytes from an Antarctic fish, Trematomus bernacchii
TLDR
Exposure to elevated temperature and to chemical inducers of the heat shock response failed to increase Hsp70 mRNA levels, HSF1 activity or the concentration of any size class of HsPS, suggesting that Hsps, inducible in nearly every other species, are expressed constitutively in the cold- adapted T. bernacchii.
Some like it hot, some like it cold: the heat shock response is found in New Zealand but not Antarctic notothenioid fishes
Transcriptional analysis of the hsp70 gene in a haloarchaeon Natrinema sp. J7 under heat and cold stress
TLDR
The results suggested that there are some special regulators of hsp70 gene in Natrinema sp.
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