Constitutive dimerization of human serotonin 5-HT4 receptors in living cells.

@article{Berthouze2005ConstitutiveDO,
  title={Constitutive dimerization of human serotonin 5-HT4 receptors in living cells.},
  author={Magali Berthouze and Mohammed A. I. Ayoub and Olivier Russo and Lucie Rivail and Sames Sicsic and Rodolphe Fischmeister and Isabelle Berque-Bestel and Ralf Jockers and Frank Lezoualc'h},
  journal={FEBS letters},
  year={2005},
  volume={579 14},
  pages={2973-80}
}
Serotonin 5-HT4 receptor isoforms are G protein-coupled receptors (GPCRs) with distinct pharmacological properties and may represent a valuable target for the treatment of many human disorders. Here, we have explored the process of dimerization of human 5-HT4 receptor (h5-HT4R) by means of co-immunoprecipitation and bioluminescence resonance energy transfer… CONTINUE READING