Constitutive cellulase production from glucose using the recombinant Trichoderma reesei strain overexpressing an artificial transcription activator.

@article{Zhang2017ConstitutiveCP,
  title={Constitutive cellulase production from glucose using the recombinant Trichoderma reesei strain overexpressing an artificial transcription activator.},
  author={Xiaoyue Zhang and Yonghao Li and Xinqing Q Zhao and Feng-Wu Bai},
  journal={Bioresource technology},
  year={2017},
  volume={223},
  pages={317-322}
}
The high cost of cellulase production presents biggest challenge in biomass deconstruction. Cellulase production by Trichoderma reesei using low cost carbon source is of great interest. In this study, an artificial transcription activator containing the Cre1 binding domain linked to the Xyr1 effector and binding domains was designed and constitutively overexpressed in T. reesei RUT C30. The recombinant strain T. reesei zxy-2 displayed constitutive cellulase production using glucose as a sole… CONTINUE READING
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