Constitutive activation of nuclear factor-kappaB is preferentially involved in the proliferation of basal-like subtype breast cancer cell lines.

@article{Yamaguchi2009ConstitutiveAO,
  title={Constitutive activation of nuclear factor-kappaB is preferentially involved in the proliferation of basal-like subtype breast cancer cell lines.},
  author={Noritaka Yamaguchi and Taku Ito and Sakura Azuma and Emi Ito and R. J. Homer A. K. Honma and Yuka Yanagisawa and Akira Nishikawa and Mika Kawamura and Jun-ichi Imai and Shinya Watanabe and Kentaro Semba and Jun-Ichiro Inoue},
  journal={Cancer science},
  year={2009},
  volume={100 9},
  pages={1668-74}
}
Constitutive nuclear factor (NF)-kappaB activation is thought to be involved in survival, invasion, and metastasis in various types of cancers. However, neither the subtypes of breast cancer cells with constitutive NF-kappaB activation nor the molecular mechanisms leading to its constitutive activation have been clearly defined. Here, we quantitatively analyzed basal NF-kappaB activity in 35 human breast cancer cell lines and found that most of the cell lines with high constitutive NF-kappaB… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

FOXC1 is a Critical Mediator of EGFR Function in Human Basal-like Breast Cancer

Annals of Surgical Oncology • 2014
View 10 Excerpts
Highly Influenced

Anti-cancer IAP antagonists promote bone metastasis: a cautionary tale

Journal of Bone and Mineral Metabolism • 2013
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…