Constitutive activation of STAT transcription factors in acute myelogenous leukemia

@article{Spiekermann2001ConstitutiveAO,
  title={Constitutive activation of STAT transcription factors in acute myelogenous leukemia},
  author={K. Spiekermann and S. Biethahn and S. Wilde and W. Hiddemann and F. Alves},
  journal={European Journal of Haematology},
  year={2001},
  volume={67}
}
Abstract: Hematopoietic growth factors (HGF) are essential for proliferation and differentiation of hematopoietic precursors and activate a distinct set of JAK‐STAT (Janus kinases‐signal transducers and activators of transcription) proteins. Previous results from our group have shown a strong expression of JAK‐STAT proteins in primary acute myelogenous leukemia (AML) blasts and AML cell lines. Here, we asked whether a constitutive activation of the JAK‐STAT pathway might be involved in the… Expand
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References

SHOWING 1-10 OF 53 REFERENCES
Differential constitutive activation between STAT‐related proteins and MAP kinase in primary acute myelogenous leukaemia
Activation of STAT3 by the c-Fes Protein-tyrosine Kinase*
Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins.
Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation
Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation
...
1
2
3
4
5
...