Constitutive NADPH oxidase 4 activity resides in the composition of the B-loop and the penultimate C terminus.

Abstract

Redox regulation of signaling molecules contributes critically to propagation of intracellular signals. The main source providing reactive oxygen species (ROS) for these physiological processes are activated NADPH oxidases (Nox/Duox family). In a pathophysiological context, some NADPH oxidase complexes produce large amounts of ROS either as part of the… (More)
DOI: 10.1074/jbc.M111.332494

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Cite this paper

@article{Loehneysen2012ConstitutiveNO, title={Constitutive NADPH oxidase 4 activity resides in the composition of the B-loop and the penultimate C terminus.}, author={Katharina von Loehneysen and Deborah Noack and Patti Hayes and Jeff Friedman and Ulla G. Knaus}, journal={The Journal of biological chemistry}, year={2012}, volume={287 12}, pages={8737-45} }