Constitutional genetic association with CALR mutations?

  title={Constitutional genetic association with CALR mutations?},
  author={L Eder-Azanza and Perry Evans and Carey Wickham and Susanna Akiki and Jos{\'e} L. Vizmanos and Andrew Chase and Nicholas C. P. Cross},
Myeloproliferative neoplasms (MPN) are driven primarily by somatically acquired mutations in JAK2, CALR or MPL. In addition, evidence from epidemiological and family studies indicates that common, low-penetrance genetic variants present in the general population contribute to the risk of developing MPN. Some of these variants have been identified, for… CONTINUE READING