Constituents of Cannabis sativa L. IV. Stability of cannabinoids in stored plant material.

@article{Turner1973ConstituentsOC,
  title={Constituents of Cannabis sativa L. IV. Stability of cannabinoids in stored plant material.},
  author={Carlton E. Turner and K. W. Hadley and Patricia S. Fetterman and Norman J. Doorenbos and Maynard W. Quimby and Coy W. Waller},
  journal={Journal of pharmaceutical sciences},
  year={1973},
  volume={62 10},
  pages={
          1601-5
        }
}
Abstract The (—)-∆ 9 - trans -tetrahydrocannabinol content of Cannabis sativa L. stored at — 18, 4, and 22 ± 1 ° decomposed at a rate of 3.83, 5.38, and 6.92%, respectively, per year, whereas the material stored at 37 and 50° showed considerable decomposition. C . satica L. stored in the absence of direct light at — 18, 4, and 22 ± 1 ° was more stable than cannabis stored under nitrogen. These data indicate that for normal research use, storage under nitrogen at 0° is not mandatory. Cannabinol… Expand
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References

SHOWING 1-6 OF 6 REFERENCES
Mississippi-grown Cannabis sativa L: preliminary observation on chemical definition of phenotype and variations in tetrahydrocannabinol content versus age, sex, and plant part.
TLDR
Nine strains of Cannabis sativa L. sativa (marijuana) were grown for research by the University of Mississippi and the cannabinoid content was determined using GLC, and the material was divided into two chemical phenotypes according to cannabinoid content. Expand
TETRAHYDROCANNABINOLS AND SYNTHETIC ANALOGS
Classical studies of the resinous cannabinoid fraction of the plant by Adams,’ Todd,2 and Cahn3 and more recently by T a y l ~ r , ~ M e c h o ~ l a m , ~ and their COworkers led to the definitiveExpand
The identification, isolation, and preservation of Δ9‐tetrahydrocannabinol (Δ9‐THC) * , †
(—)‐trans‐Δ9‐Tetrahydrocannabinol (Δ9‐THC) was isolated from marihuana plant extract, by adsorptive column and glc. The adsorptive column chromatography method consisted of chromatographing marihuanaExpand
Constituents of Cannabis sativa L. 3. Clear and discrete separation of cannabidiol and cannabichromene.
Synthetic cannabidiol and cannabichromene were discretely separated by GLC using their trimethylsilyl ether derivatives. The mono and disilylated derivatives of cannabidiol were identified. ThisExpand
Origin of cannabinol