Constant Mean Viral Copy Number per Infected Cell in Tissues Regardless of High, Low, or Undetectable Plasma HIV RNA

@article{Hockett1999ConstantMV,
  title={Constant Mean Viral Copy Number per Infected Cell in Tissues Regardless of High, Low, or Undetectable Plasma  HIV RNA },
  author={Richard Dean Hockett and J. Michael Kilby and Cynthia A. Derdeyn and Michael S Saag and Michael Sillers and Kathleen Squires and Scott Chiz and Martin A. Nowak and George M. Shaw and R. Pat Bucy},
  journal={The Journal of Experimental Medicine},
  year={1999},
  volume={189},
  pages={1545 - 1554}
}
Quantitative analysis of the relationship between virus expression and disease outcome has been critical for understanding HIV-1 pathogenesis. Yet the amount of viral RNA contained within an HIV-expressing cell and the relationship between the number of virus-producing cells and plasma virus load has not been established or reflected in models of viral… CONTINUE READING