Consolidation of learning strategies during spatial working memory task requires protein synthesis in the prefrontal cortex.

@article{Touzani2007ConsolidationOL,
  title={Consolidation of learning strategies during spatial working memory task requires protein synthesis in the prefrontal cortex.},
  author={Khalid Touzani and Sathyanarayanan V. Puthanveettil and Eric R Kandel},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 13},
  pages={5632-7}
}
Working memory is a temporary memory store where information is held briefly until the appropriate behavior is produced. However, the improvement in the performance of working memory tasks with practice over days points to the existence of a long-lasting component associated with learning strategies that lead to optimal performance. Here we show that the improvement in the performance of mice in a radial maze working memory task required the integrity of the medial prefrontal cortex (mPFC). We… CONTINUE READING
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