Consolidation of human memory over decades revealed by functional magnetic resonance imaging

@article{Haist2001ConsolidationOH,
  title={Consolidation of human memory over decades revealed by functional magnetic resonance imaging},
  author={Frank Haist and Jane Bowden Gore and Hui Mao},
  journal={Nature Neuroscience},
  year={2001},
  volume={4},
  pages={1139-1145}
}
Medial temporal lobe (MTL) lesions typically produce retrograde amnesia characterized by the disproportionate loss of recently acquired memories. Temporally graded memory loss is interpreted traditionally as evidence for a consolidation process guided by the MTL. Here, using functional magnetic resonance imaging (fMRI), we show temporally graded changes in MTL activity in healthy older adults taking a famous faces remote memory test. Evidence for temporally graded change in the hippocampal… 
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