Considerations when assessing heterogeneity of treatment effect in patient-centered outcomes research.

Abstract

When baseline risk of an outcome varies within a population, the effect of a treatment on that outcome will vary on at least one scale (e.g., additive, multiplicative). This treatment effect heterogeneity is of interest in patient-centered outcomes research. Based on a literature review and solicited expert opinion, we assert: 1) Treatment effect… (More)
DOI: 10.1016/j.jclinepi.2018.04.005

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