Considerations in binding diblock copolymers on hydrophilic alginate beads for providing an immunoprotective membrane

@inproceedings{Spasojevi2014ConsiderationsIB,
  title={Considerations in binding diblock copolymers on hydrophilic alginate beads for providing an immunoprotective membrane},
  author={Milica Spasojevi{\'c} and Swapnil V. Bhujbal and Genaro Paredes and Bart J de Haan and Arend Jan Schouten and Paul de Vos},
  booktitle={Journal of biomedical materials research. Part A},
  year={2014}
}
Alginate-based microcapsules are being proposed for treatment of many types of diseases. A major obstacle however in the successes is that these capsules are having large lab-to-lab variations. To make the process more reproducible, we propose to cover the surface of alginate capsules with diblock polymers that can form polymer brushes. In the present study, we describe the stepwise considerations for successful application of diblock copolymer of polyethylene glycol (PEG) and poly-L-lysine… CONTINUE READING
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