Consider the lung as a sensory organ: A tip from pulmonary neuroendocrine cells.
@article{Garg2019ConsiderTL, title={Consider the lung as a sensory organ: A tip from pulmonary neuroendocrine cells.}, author={Ankur Garg and Pengfei Sui and Jamie M. Verheyden and Lisa R. Young and Xin Sun}, journal={Current topics in developmental biology}, year={2019}, volume={132}, pages={ 67-89 } }
32 Citations
Less Is More: Rare Pulmonary Neuroendocrine Cells Function as Critical Sensors in Lung.
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The physiological relevance of pulmonary neuroendocrine cells, rare airway epithelial cells that form intrapulmonary sensory organs, abnormalities of which are associated with several pulmonary disorders, such as asthma and lung cancer, are highlighted.
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It is demonstrated in vivo that PNECs act as precise airway sensors that elicit immune responses via neuropeptides, suggesting that the PNec and Neuropeptide abnormalities documented in a wide array of pulmonary diseases may profoundly affect symptoms and progression.
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