Conserved small non-coding RNAs that belong to the sigmaE regulon: role in down-regulation of outer membrane proteins.

@article{Johansen2006ConservedSN,
  title={Conserved small non-coding RNAs that belong to the sigmaE regulon: role in down-regulation of outer membrane proteins.},
  author={Jesper S. Johansen and Anders Aamann Rasmussen and Martin Overgaard and P. Valentin-Hansen},
  journal={Journal of molecular biology},
  year={2006},
  volume={364 1},
  pages={
          1-8
        }
}
Enteric bacteria respond to misfolded proteins by activating the transcription of "heat shock" genes. These genes are arranged in two major regulons controlled by the alternative sigma factors sigmaH and sigmaE. The two transcription factors coordinate the stress response in different cellular compartments; the sigmaH regulon is induced by stress in the cytoplasm whereas the sigmaE regulon is activated by stress signals in the cell envelope. In Escherichia coli sigmaE plays a central role in… CONTINUE READING

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