Conserved patterns in bacterial genomes: A conundrum physically tailored by evolutionary tinkering

@article{Junier2014ConservedPI,
  title={Conserved patterns in bacterial genomes: A conundrum physically tailored by evolutionary tinkering},
  author={Ivan Junier},
  journal={Computational biology and chemistry},
  year={2014},
  volume={53 Pt A},
  pages={
          125-33
        }
}
  • Ivan Junier
  • Published 2014
  • Computer Science, Medicine, Biology
  • Computational biology and chemistry
  • The proper functioning of bacteria is encoded in their genome at multiple levels or scales, each of which is constrained by specific physical forces. At the smallest spatial scales, interatomic forces dictate the folding and function of proteins and nucleic acids. On longer length scales, stochastic forces emerging from the thermal jiggling of proteins and RNAs impose strong constraints on the organization of genes along chromosomes, more particularly in the context of the building of… CONTINUE READING

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