Conserved loop sequence of helix 69 in Escherichia coli 23 S rRNA is involved in A-site tRNA binding and translational fidelity.

@article{Hirabayashi2006ConservedLS,
  title={Conserved loop sequence of helix 69 in Escherichia coli 23 S rRNA is involved in A-site tRNA binding and translational fidelity.},
  author={Naomi Hirabayashi and Neuza Satomi Sato and Tsutomu Suzuki},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 25},
  pages={
          17203-11
        }
}
Ribosomal (r) RNAs play a crucial role in the fundamental structure and function of the ribosome. Helix 69 (H69) (position 1906-1924), a highly conserved stem-loop in domain IV of the 23 S rRNA of bacterial 50 S subunits, is located on the surface for intersubunit association with the 30 S subunit by connecting with helix 44 of 16 S rRNA with the bridge B2a. H69 directly interacts with A/T-, A-, and P-site tRNAs during each translation step. To investigate the functional importance of the… CONTINUE READING
Highly Cited
This paper has 33 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-3 of 3 references

A short course in bacterial genetics: a laboratory manual and handbook for Escherichia coli and related bacteria., Plainview, N.Y., Cold Spring Harbor Laboratory

  • J. H. Miller
  • 1992
Highly Influential
3 Excerpts

Genes Cells 6, 1019-1030 by gest on A uust 31

  • T. Hanada, T. Suzuki, T. Yokogawa, C. Takemoto-Hori, M. Sprinzl, K. Watanabe
  • 2001
1 Excerpt

Isolation and analysis of ribosomes from prokaryotes, eukaryotes, and organelles, Ribosomes and Protein Synthesis, A Practical Approach. Ribosomes and Protein Synthesis, A Practical Approach

  • G. Spedding
  • Edited by Spedding,
  • 1990
1 Excerpt