Conserved genomic organisation of Group B Sox genes in insects.

  title={Conserved genomic organisation of Group B Sox genes in insects.},
  author={Carol McKimmie and Gertrud Woerfel and Steven Russell},
  journal={BMC Genetics},
  pages={26 - 26}
Sox domain containing genes are important metazoan transcriptional regulators implicated in a wide rage of developmental processes. The vertebrate B subgroup contains the Sox1, Sox2 and Sox3 genes that have early functions in neural development. Previous studies show that Drosophila Group B genes have been functionally conserved since they play essential roles in early neural specification and mutations in the Drosophila Dichaete and SoxN genes can be rescued with mammalian Sox genes. Despite… CONTINUE READING