Conserved genetic programs in insect and mammalian brain development.

  title={Conserved genetic programs in insect and mammalian brain development.},
  author={Frank Hirth and Heinrich Reichert},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  volume={21 8},
In recent years it has become evident that the developmental regulatory genes involved in patterning the embryonic body plan are conserved throughout the animal kingdom. Striking examples are the orthodenticle (otd/Otx) gene family and the Hox gene family, both of which act in the specification of anteroposterior polarity along the embryonic body axis. Studies carried out in Drosophila and mouse now demonstrate that these genes are also involved in the formation of the insect and mammalian… CONTINUE READING

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