Conserved association of Argonaute 1 and 2 proteins with miRNA and siRNA pathways throughout insect evolution, from cockroaches to flies.
@article{Rubio2018ConservedAO, title={Conserved association of Argonaute 1 and 2 proteins with miRNA and siRNA pathways throughout insect evolution, from cockroaches to flies.}, author={Mercedes Rubio and Jos{\'e} Luis Maestro and Maria-Dolors Piulachs and Xavier Belles}, journal={Biochimica et biophysica acta. Gene regulatory mechanisms}, year={2018}, volume={1861 6}, pages={ 554-560 } }
12 Citations
siRNA enrichment in Argonaute 2-depleted Blattella germanica.
- BiologyBiochimica et biophysica acta. Gene regulatory mechanisms
- 2021
siRNA enrichment in Argonaute 2-depleted Blattella germanica
- BiologybioRxiv
- 2021
Light is shed on an extremely useful process for reverse genetics in laboratories, in addition to the design of more effective, specific, and eco-friendly pest-control strategies, on cockroach Blattella germanica.
Unravelling the developmental and functional significance of an ancient Argonaute duplication
- BiologybioRxiv
- 2020
This work characterized the functions of two Argonaute paralogs in the sea anemone Nematostella vectensis of the phylum Cnidaria, which is separated from bilaterians by ∼600 million years, and postulate a novel model for evolution of miRNA precursors inSea anemones and their relatives, revealing alternative trajectories for metazoan miRNA evolution.
Tissue-Specific Knockdown of Genes of the Argonaute Family Modulates Lifespan and Radioresistance in Drosophila melanogaster
- BiologyInternational journal of molecular sciences
- 2021
Surprisingly, piwi knockdown in both the fat body and the nervous system causes a lifespan increase and changes in radioresistance depend on the tissue in which the gene was knocked out.
Dissecting protein domain variability in the core RNA interference machinery of five insect orders
- BiologyRNA biology
- 2020
The results show that four domains, namely dsrm, Helicase, PAZ and Ribonuclease III are the main contributors of protein variability in the RNAi machinery across different insect orders, and several order-specific singularities indicate that lepidopterans have evolved differently from other insect orders.
MicroRNAs: From Mechanism to Organism
- BiologyFrontiers in Cell and Developmental Biology
- 2020
Focus on selected animal models and through the lens of evolution, canonical mechanisms in miRNA biology and their variations are highlighted, providing updated insight that will ultimately help to understand the contribution of miRNAs to the development and physiology of multicellular organisms.
Double-stranded RNA binding protein, Staufen, is required for the initiation of RNAi in coleopteran insects
- BiologyProceedings of the National Academy of Sciences
- 2018
Experiments in two coleopteran insects showed the requirement of StaufenC for RNAi, especially for processing of double-stranded RNA (dsRNA) to small interfering RNA, which will help improve RNAi in noncoleoptera insects and manage RNAi resistance in colepteran insects.
Genome-wide identification of miRNAs and target regulatory network in the invasive ectoparasitic mite Varroa destructor.
- BiologyGenomics
- 2021
The critical impacts of small RNA biogenesis proteins on aging, longevity and age-related diseases
- BiologyAgeing Research Reviews
- 2020
Genome-wide identification and analysis of genes associated with RNA interference in Bemisia tabaci.
- BiologyPest management science
- 2019
This study annotated and validated genes involved in B. tabaci RNAi and identified and analyzed candidate genes in the RNAi pathway to understand theRNAi mechanism and provide a basis for the application of RNAi in pest management.
References
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