Conserved TCR usage by HLA-Cw* 1601-restricted T cell clones recognizing melanoma antigens.

@article{Farina1996ConservedTU,
  title={Conserved TCR usage by HLA-Cw* 1601-restricted T cell clones recognizing melanoma antigens.},
  author={Cinthia Farina and Pierre van der Bruggen and Pascale Bo{\"e}l and Giorgio Parmiani and Marialuisa Sensi},
  journal={International immunology},
  year={1996},
  volume={8 9},
  pages={
          1463-6
        }
}
In this study we determined TCR alpha and beta chain nucleotide sequences of HLA-Cw* 1601-restricted cytoxic T lymphocyte (CTL) clones obtained from the peripheral blood lymphocytes (PBL) of a melanoma patient. These clones were previously shown to be involved in the recognition of melanoma-associated antigenic epitopes SAYGEPRKL and AARAVFLAL encoded by gene MAGE-1 and BAGE respectively. All (3/3) anti-MAGE-1 CTL clones displayed TCRBV5 usage and one clonotype was found twice, > 1 year apart… 
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