Conserved Synteny As a Measure of Genomic Distance

  title={Conserved Synteny As a Measure of Genomic Distance},
  author={David Sankoff and Joseph H. Nadeau},
  journal={Discrete Applied Mathematics},
The number of chromosomal segments conserved during the evolution of two species can be used to measure their genomic distance. The number of conserved segments containing homologous genes can be estimated by comparing synteny relations within and between the two genomes. There are three sources of underestimation, however. The first stems from conserved segments in which genes are yet to be identified in one or both species. The second results from repeated translocations or transpositions… CONTINUE READING

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