Conserved C-terminus of the phosphatase CheZ is a binding domain for the chemotactic response regulator CheY.

@article{Blat1996ConservedCO,
  title={Conserved C-terminus of the phosphatase CheZ is a binding domain for the chemotactic response regulator CheY.},
  author={Yuval Blat and Michael Eisenbach},
  journal={Biochemistry},
  year={1996},
  volume={35 18},
  pages={
          5679-83
        }
}
CheZ is the phosphatase of the chemotactic response regulator, CheY. There are three conserved domains on CheZ. Here we determined the function of the C-terminal domain (residues 202-214). A truncated form of CheZ, missing residues 202-214, hardly bound to the phosphorylated form of CheY. Conversely, a peptide composed of the last 19 amino acid residues of the CheZ (residues 196-214), generated by tryptic digestion, bound specifically to the phosphorylated form of CheY. This was demonstrated by… CONTINUE READING
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Interaction of CheY with the C-terminal peptide of CheZ.

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