Corpus ID: 24812123

Conservative surgical management of necrotic tissues following meningococcal sepsis: case report of a child treated with hyperbaric oxygen.

  title={Conservative surgical management of necrotic tissues following meningococcal sepsis: case report of a child treated with hyperbaric oxygen.},
  author={Ines Taka{\vc} and Slavica Kvolik and Dalibor Divkovi{\'c} and Jasenka Kalajdzic-Candrlic and Silvija Puseljic and Senka I{\vz}akovi{\'c}},
  journal={Undersea \& hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc},
  volume={37 2},
  • I. Takač, S. Kvolik, +3 authors Senka Ižaković
  • Published 1 March 2010
  • Medicine
  • Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
This article presents the case of a 5-month-old infant, who survived a fulminant meningococcal sepsis with purpura fulminans, septic shock and severe DIC with gastrointestinal bleeding. Amputation and reconstructive surgery were considered to treat the multiple skin and limb necroses at high risk of superinfection, but the surgical intervention was delayed due to the extremely doubtful outcome. On Day 10 after the onset of the disease, a hemodynamic improvement was achieved. The baby overcame… Expand
Meningococcal purpura fulminans in children: I. Initial orthopedic management
By performing amputations and skin coverage some time after the acute phase, the aim of this study was to look at the predictive factors in orthopedic outcome in light of the initial surgical management in children surviving initial resuscitation. Expand
[Varicella-associated purpura fulminans and deep vein thrombosis: a pediatric case report].
  • A. Baur, R. Pouyau, +5 authors Y. Gillet
  • Medicine
  • Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
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A 4-year-old boy with no medical history who presented with purpura on the legs 10 days after chicken pox eruption and was treated with unfractionated heparin is illustrated and the utility of thrombophilia testing is emphasized in order to better adapt treatment. Expand
Australian Paediatric Hyperbaric Oxygen Therapy 1998–2011
It is indicated that provision of hyperbaric oxygen therapy to children is feasible in major regionalHyperbaric units and is associated with low complication rates, which requires significant cooperation between paediatric, intensive care andhyperbaric consultants. Expand
Four Extremity Amputation and Bionic Prosthesis Supply after Disseminated Intravascular Coagulation: A Follow-Up on Functionality and Quality of Life after Bionic Prosthesis Supply
Supplying bionic prostheses after DIC yielded sufficient to moderate results, however, prothesis weight, signal transmission disorders, and repeated functional failures were suboptimal. Expand
Pediatric hyperbaric oxygen therapy in Victoria, 1998–2010
  • G. Frawley, A. Fock
  • Medicine
  • Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
  • 2012
Objectives: The aim of this review is to identify clinical conditions currently treated in a pediatric population referred to the Alfred hyperbaric unit, to describe outcomes, and detail anyExpand
Invasive Meningococcal Disease: A Review
It is important to be able to correctly recognize patients withasive meningococcal disease for early and aggressive management and prevention by vaccination remains the best public health measure to tackle this deadly infection. Expand
Hyperbaric medicine in Rijeka 25 years after the publication of the first Croatian list of indications for hyperbaric oxygenation
Current Croatian List of indications for hyperbaric oxygenation (HBO2T) should be edited to meet the recommendations set forth by the European consensus list for HBO2T. Expand
Acute Hyperbaric Oxygenation, Contrary to Intermittent Hyperbaric Oxygenation, Adversely Affects Vasorelaxation in Healthy Sprague-Dawley Rats due to Increased Oxidative Stress
Assessment of endothelium-dependent vasorelaxation, measuring superoxide production in the aorta and femoral artery, and determining antioxidative enzyme expression and activity in aortas of male Sprague-Dawley rats and in vitro in the absence/presence of NOS inhibitor L-NAME and superoxide scavenger TEMPOL found oxidative stress andsuperoxide production were increased in the A-HBO2 group compared to all other groups. Expand
Purpura fulminans post-varicelleux et thrombose veineuse : à propos d’un cas pédiatrique
Ces donnees biologiques mettaient en evidence une coagulation intravasculaire disseminee (CIVD) avec un effondrement des proteines S et C et the presence d’anticorps anti-proteine S. Expand
Utjecaj hiperbarične oksigenacije na promjenu serumske koncentracije oksidiranih lipoproteina niske gustoće i naprednih oksidiranih proteinskih proizvoda kod Sprague-Dawley štakora
CILJ ISTRAŽIVANJA: Cilj ovog istraživanja bio je ispitati promjenu serumske koncentracije naprednih oksidiranih proteinskih proizvoda (AOPP) i oksid


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The data would suggest that children requiring surgery for purpura fulminans achieve age-appropriate milestones and are primarily limited by their physical disability related to amputations, scarring, and abnormal bone growth. Expand
Current management of purpura fulminans: a multicenter study.
Fasciotomies during the initial management of patients diagnosed with purpura fulminans may reduce the depth of soft-tissue involvement and the extent of amputations. Expand
Adjuvant hyperbaric oxygen therapy (HBO2)for treatment of necrotizing fasciitis reduces mortality and amputation rate.
Compared to national reports of outcomes with "standard" regimens for necrotizing fasciitis, the experience with HBO2, adjunctive to comprehensive and aggressive management, demonstrates reduced mortality and morbidity. Expand
Plastic surgery management in pediatric meningococcal-induced purpura fulminans.
Conservative therapy to the wounds appears to be the best course in the initial, critical phase, as long as no active local purulence is found and nonviable tissue margins are delineated. Expand
Critical Illness and Amputation in Meningococcal Septicemia: Is Life Worth Saving?
The surprisingly good outcomes reported should discourage clinicians from withdrawing intensive care support because of presumed poor outcomes after multiple amputations in severe meningococcal disease. Expand
Hyperbaric oxygenation was used in the treatment of purpura gangrenosa and the subsequent complete resolution of the peripheral lesions with loss of tissue is unusual in this severe and commonly fatal illness. Expand
Hyperoxia and infection.
  • H. Hopf, J. Holm
  • Medicine
  • Best practice & research. Clinical anaesthesiology
  • 2008
The basic science underlying these observations, along with the clinical data that support the use of hyperoxia in preventing and treating infections, are reviewed. Expand
Synergy of HBO2 and a local antibiotic carrier for experimental osteomyelitis due to Staphylococcus aureus in rats.
No complete healing of the infection was achieved with the flexible collagen sponge characterized by pronounced and rapid release of gentamicin, but in combination with hyperbaric oxygen an additive effect was attained and thus a significant improvement of treatment. Expand
Effects of hyperbaric oxygen therapy on experimental burn wound healing in rats: a randomized controlled study.
  • I. Bilic, N. Petri, +4 authors B. Bota
  • Medicine
  • Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
  • 2005
A significant reduction of the post-burn edema after treatment with HBO2 was found and data further support earlier conclusions that HBO2 is beneficial in the healing of burn wounds. Expand
Textbook Of Hyperbaric Medicine
Part 1 Basic aspects: history of hyperbaric medicine physical, physiological and biochemical aspects of hyperbaric oxygenation effect of diving and high pressure environments on the human bodyExpand