Conservation of the organization of five tightly clustered genes over 600 million years of divergent evolution.

Abstract

The organization of the mouse surfeit locus is unusual in that it contains six housekeeping genes (Surf-1-Surf-6), which are unrelated by sequence homology, in the tightest mammalian gene cluster thus far described. A maximum of only 73 base pairs separates any two of the four well-characterized genes, and two of the genes overlap at their 3' ends. The… (More)

Topics

Cite this paper

@article{Colombo1992ConservationOT, title={Conservation of the organization of five tightly clustered genes over 600 million years of divergent evolution.}, author={P. Colombo and Jeff Yon and Kathryn Garson and M. Fried}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1992}, volume={89 14}, pages={6358-62} }