Conservation of the binding site for the arginine repressor in all bacterial lineages

@article{Makarova2000ConservationOT,
  title={Conservation of the binding site for the arginine repressor in all bacterial lineages},
  author={Kira S. Makarova and Andrey A. Mironov and Mikhail S. Gelfand},
  journal={Genome Biology},
  year={2000},
  volume={2},
  pages={research0013.1 - research0013.8}
}
The arginine repressor ArgR/AhrC is a transcription factor universally conserved in bacterial genomes. Its recognition signal (the ARG box), a weak palindrome, is also conserved between genomes, despite a very low degree of similarity between individual sites within a genome. Thus, the arginine repressor is different from two other universal transcription factors - HrcA, whose recognition signal is very strongly conserved both within and between genomes, and LexA/DinR, whose signal is strongly… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 50 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 40 references

The use of gene clusters to infer functional coupling.

Proceedings of the National Academy of Sciences of the United States of America • 1999

Similar Papers

Loading similar papers…