Conservation of amino-acid sequence motifs in lentivirus Vif proteins

The nonstructural/regulatory genes of human immunodeficiency virus type 1 (HIV-1) and other lentiviruses are believed to play an important role in the replication and pathogenesis of these viruses. In HIV-1 and other lentiviruses, thevif (viral infectivity factor) open reading frame (ORF) (also termedsor orQ in some lentivirus genomes) is located in the… CONTINUE READING