Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee

@article{Hughes2005ConservationOY,
  title={Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee},
  author={J. Hughes and H. Skaletsky and Tatyana Pyntikova and P. Minx and T. Graves and S. Rozen and R. Wilson and D. Page},
  journal={Nature},
  year={2005},
  volume={437},
  pages={100-103}
}
  • J. Hughes, H. Skaletsky, +5 authors D. Page
  • Published 2005
  • Biology, Medicine
  • Nature
  • The human Y chromosome, transmitted clonally through males, contains far fewer genes than the sexually recombining autosome from which it evolved. The enormity of this evolutionary decline has led to predictions that the Y chromosome will be completely bereft of functional genes within ten million years. Although recent evidence of gene conversion within massive Y-linked palindromes runs counter to this hypothesis, most unique Y-linked genes are not situated in palindromes and have no gene… CONTINUE READING
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    References

    SHOWING 1-10 OF 30 REFERENCES
    DNA sequence and comparative analysis of chimpanzee chromosome 22
    • 226
    • PDF
    The degenerate Y chromosome--can conversion save it?
    • J. Graves
    • Biology, Medicine
    • Reproduction, fertility, and development
    • 2004
    • 41
    • PDF
    A physical map of the human Y chromosome
    • 225
    • PDF
    Four evolutionary strata on the human X chromosome.
    • 822
    • PDF
    The degeneration of Y chromosomes.
    • 752
    • PDF