Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee

  title={Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee},
  author={J. Hughes and H. Skaletsky and Tatyana Pyntikova and P. Minx and T. Graves and S. Rozen and R. Wilson and D. Page},
  • J. Hughes, H. Skaletsky, +5 authors D. Page
  • Published 2005
  • Biology, Medicine
  • Nature
  • The human Y chromosome, transmitted clonally through males, contains far fewer genes than the sexually recombining autosome from which it evolved. The enormity of this evolutionary decline has led to predictions that the Y chromosome will be completely bereft of functional genes within ten million years. Although recent evidence of gene conversion within massive Y-linked palindromes runs counter to this hypothesis, most unique Y-linked genes are not situated in palindromes and have no gene… CONTINUE READING
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