Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee

@article{Hughes2005ConservationOY,
  title={Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee},
  author={J. F. Hughes and Helen Skaletsky and Tatyana Pyntikova and Patrick Minx and Tina Graves and Steve Rozen and Richard K. Wilson and David C. Page},
  journal={Nature},
  year={2005},
  volume={437},
  pages={100-103}
}

• J. F. Hughes, Helen Skaletsky, +5 authors David C. Page
• Published 2005 in Nature
• DOI:10.1038/nature04101

The human Y chromosome, transmitted clonally through males, contains far fewer genes than the sexually recombining autosome from which it evolved. The enormity of this evolutionary decline has led to predictions that the Y chromosome will be completely bereft of functional genes within ten million years. Although recent evidence of gene conversion within massive Y-linked palindromes runs counter to this hypothesis, most unique Y-linked genes are not situated in palindromes and have no gene… CONTINUE READING

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