Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee

@article{Hughes2005ConservationOY,
  title={Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee},
  author={J. Hughes and H. Skaletsky and Tatyana Pyntikova and P. Minx and Tina Graves and S. Rozen and R. Wilson and D. Page},
  journal={Nature},
  year={2005},
  volume={437},
  pages={100-103}
}
The human Y chromosome, transmitted clonally through males, contains far fewer genes than the sexually recombining autosome from which it evolved. The enormity of this evolutionary decline has led to predictions that the Y chromosome will be completely bereft of functional genes within ten million years. Although recent evidence of gene conversion within massive Y-linked palindromes runs counter to this hypothesis, most unique Y-linked genes are not situated in palindromes and have no gene… Expand
174 Citations
Comparative analysis of mammalian Y chromosomes illuminates ancestral structure and lineage-specific evolution.
  • 84
  • Highly Influenced
  • PDF
Novel Gene Acquisition on Carnivore Y Chromosomes
  • 76
  • PDF
Sequencing of rhesus macaque Y chromosome clarifies origins and evolution of the DAZ (Deleted in AZoospermia) genes
  • 23
  • PDF
Evolution of X-Degenerate Y Chromosome Genes in Greater Apes: Conservation of Gene Content in Human and Gorilla, But Not Chimpanzee
  • 28
  • Highly Influenced
The evolutionary history of human and chimpanzee Y-chromosome gene loss.
  • 28
  • PDF
Extinction of chromosomes due to specialization is a universal occurrence
  • 1
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 30 REFERENCES
DNA sequence and comparative analysis of chimpanzee chromosome 22
  • 226
  • PDF
The degenerate Y chromosome--can conversion save it?
  • J. Graves
  • Biology, Medicine
  • Reproduction, fertility, and development
  • 2004
  • 41
  • PDF
A physical map of the human Y chromosome
  • 226
  • PDF
Four evolutionary strata on the human X chromosome.
  • 831
  • PDF
The degeneration of Y chromosomes.
  • 760
...
1
2
3
...