• DOI:10.1038/nature04101
Corpus ID: 4418662

Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee

@article{Hughes2005ConservationOY,
  title={Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee},
  author={J. Hughes and H. Skaletsky and Tatyana Pyntikova and P. Minx and Tina Graves and S. Rozen and R. Wilson and D. Page},
  journal={Nature},
  year={2005},
  volume={437},
  pages={100-103}
}

• J. Hughes, H. Skaletsky, +5 authors D. Page
• Published 2005
• Biology, Medicine
• Nature

The human Y chromosome, transmitted clonally through males, contains far fewer genes than the sexually recombining autosome from which it evolved. The enormity of this evolutionary decline has led to predictions that the Y chromosome will be completely bereft of functional genes within ten million years. Although recent evidence of gene conversion within massive Y-linked palindromes runs counter to this hypothesis, most unique Y-linked genes are not situated in palindromes and have no gene… Expand

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