Conservation of Regional Variation in Sex-Specific Sex Chromosome Regulation.

@article{Wright2015ConservationOR,
  title={Conservation of Regional Variation in Sex-Specific Sex Chromosome Regulation.},
  author={Alison E. Wright and Fabian Zimmer and Peter W. Harrison and Judith E. Mank},
  journal={Genetics},
  year={2015},
  volume={201 2},
  pages={
          587-98
        }
}
Regional variation in sex-specific gene regulation has been observed across sex chromosomes in a range of animals and is often a function of sex chromosome age. The avian Z chromosome exhibits substantial regional variation in sex-specific regulation, where older regions show elevated levels of male-biased expression. Distinct sex-specific regulation also has been observed across the male hypermethylated (MHM) region, which has been suggested to be a region of nascent dosage compensation… CONTINUE READING
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