Conservation and purifying selection of transcribed genes located in a rice centromere.

@article{Fan2011ConservationAP,
  title={Conservation and purifying selection of transcribed genes located in a rice centromere.},
  author={Chuanzhu Fan and Jason G Walling and Jianwei Zhang and Cory D Hirsch and Jiming Jiang and Rod A Wing},
  journal={The Plant cell},
  year={2011},
  volume={23 8},
  pages={2821-30}
}
Recombination is strongly suppressed in centromeric regions. In chromosomal regions with suppressed recombination, deleterious mutations can easily accumulate and cause degeneration of genes and genomes. Surprisingly, the centromere of chromosome8 (Cen8) of rice (Oryza sativa) contains several transcribed genes. However, it remains unclear as to what selective forces drive the evolution and existence of transcribed genes in Cen8. Sequencing of orthologous Cen8 regions from two additional Oryza… CONTINUE READING

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