• Corpus ID: 16576645

Conservation and losses of avian non-coding RNA loci

  title={Conservation and losses of avian non-coding RNA loci},
  author={Paul P. Gardner and Mario Fasold and Sarah W. Burge and Maria Ninova and Jana Hertel and Stephanie Kehr and Tammy E. Steeves and Sam Griffiths-Jones and Peter F. Stadler},
  journal={arXiv: Genomics},
Here we present the results of a large-scale bioinformatic annotation of non-coding RNA loci in 48 avian genomes. Our approach uses probabilistic models of hand-curated families from the Rfam database to infer conserved RNA families within each avian genome. We supplement these annotations with predictions from the tRNA annotation tool, tRNAscan-SE and microRNAs from miRBase. We show that a number of lncRNA-associated loci are conserved between birds and mammals, including several intriguing… 

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