Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part IX: Changes in the tracheobronchial epithelium, pulmonary acinus, and lung antioxidant enzyme activity.

@article{Pinkerton1995ConsequencesOP,
  title={Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part IX: Changes in the tracheobronchial epithelium, pulmonary acinus, and lung antioxidant enzyme activity.},
  author={Kent E. Pinkerton and Margaret G. Menache and Charles G. Plopper},
  journal={Research report},
  year={1995},
  volume={65 Pt 8-9},
  pages={41-98; discussion 99-110}
}
The effect of ozone on the respiratory system is not confined to a single region or a specific cell type. Ozone-induced injury can occur at all levels of the respiratory system. However, the effects of this oxidant gas throughout the tracheobronchial tree and the lung parenchyma can be highly variable. The doses of ozone delivered to the various regions may also be different, and these differences may have a significant effect on the extent of injury. To examine the effects of chronic exposure… CONTINUE READING