Consequences of prenatal toxin exposure for mental health in children and adolescents

  title={Consequences of prenatal toxin exposure for mental health in children and adolescents},
  author={Justin H. G. Williams and Louise C. Ross},
  journal={European Child \& Adolescent Psychiatry},
Drug use during pregnancy is common and the developing foetus may be exposed to a range of environmental toxins that have long-term consequences for neurodevelopment. We conducted a systematic review of the literature to explore the results of longitudinal cohort studies that have examined this question. Out of 2,977 abstracts identified, 7 previous systematic reviews and 95 original articles met further selection criteria. These mostly addressed the neurodevelopmental effects of exposure to… 
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Prenatal exposure to polychlorinated biphenyls and attention at school age.
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Cognitive outcomes of preschool children with prenatal cocaine exposure.
Prenatal cocaine exposure was not associated with lower full-scale, verbal, or performance IQ scores but was associated with an increased risk for specific cognitive impairments and lower likelihood of IQ above the normative mean at 4 years.
Prenatal exposure to methylmercury and child development: influence of social factors.
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It is found that ETS exposure could cause subtle changes in children's neurodevelopment and behavior, however, studies to date are difficult to interpret because of the unknown influence of uncontrolled confounding factors, imprecision in measurements of smoking exposure, and collinearity of pre- and postnatal maternal smoking.
Consequences of lead exposure and iron supplementation on childhood development at age 4 years.
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Prenatal smoking and early childhood conduct problems: testing genetic and environmental explanations of the association.
Observed associations between prenatal smoking and childhood conduct problems are likely to be heavily confounded with other known risks for children's behavioral development.