Consequences of prenatal toxin exposure for mental health in children and adolescents

@article{Williams2006ConsequencesOP,
  title={Consequences of prenatal toxin exposure for mental health in children and adolescents},
  author={Justin H. G. Williams and Louise C. Ross},
  journal={European Child \& Adolescent Psychiatry},
  year={2006},
  volume={16},
  pages={243-253}
}
Drug use during pregnancy is common and the developing foetus may be exposed to a range of environmental toxins that have long-term consequences for neurodevelopment. We conducted a systematic review of the literature to explore the results of longitudinal cohort studies that have examined this question. Out of 2,977 abstracts identified, 7 previous systematic reviews and 95 original articles met further selection criteria. These mostly addressed the neurodevelopmental effects of exposure to… 
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References

SHOWING 1-10 OF 76 REFERENCES
Caffeine use during pregnancy and child outcome: a 7-year prospective study.
Prenatal exposure to polychlorinated biphenyls and attention at school age.
TLDR
These findings are consistent with earlier reports of greater vulnerability to prenatal PCB exposure in children who were not breast fed and are not clear whether the protection offered by breast-feeding is caused by nutrients in breast milk or better quality of intellectual stimulation often provided by Breast-feeding mothers.
Cognitive outcomes of preschool children with prenatal cocaine exposure.
TLDR
Prenatal cocaine exposure was not associated with lower full-scale, verbal, or performance IQ scores but was associated with an increased risk for specific cognitive impairments and lower likelihood of IQ above the normative mean at 4 years.
Prenatal exposure to methylmercury and child development: influence of social factors.
Association of prenatal maternal or postnatal child environmental tobacco smoke exposure and neurodevelopmental and behavioral problems in children.
TLDR
It is found that ETS exposure could cause subtle changes in children's neurodevelopment and behavior, however, studies to date are difficult to interpret because of the unknown influence of uncontrolled confounding factors, imprecision in measurements of smoking exposure, and collinearity of pre- and postnatal maternal smoking.
Consequences of lead exposure and iron supplementation on childhood development at age 4 years.
Foster-Placed and Adopted Children Exposed In Utero to Opiates and Other Substances: Prediction and Outcome at Four and a Half Years
  • Vibeke Moe
  • Psychology
    Journal of developmental and behavioral pediatrics : JDBP
  • 2002
TLDR
The findings showed that although the mean cognitive scores were within normal limits at age 4½ years, a special weakness in the area of visual-motor and perceptual abilities was detected among the substance-exposed children, indicating that these areas of performance are especially sensitive to the effect of prenatal adversity.
Prenatal smoking and early childhood conduct problems: testing genetic and environmental explanations of the association.
TLDR
Observed associations between prenatal smoking and childhood conduct problems are likely to be heavily confounded with other known risks for children's behavioral development.
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