Consequences of polyspermy in man.

@article{Angell1986ConsequencesOP,
  title={Consequences of polyspermy in man.},
  author={Roslyn R. Angell and Allan A. Templeton and Ioannis E Messinis},
  journal={Cytogenetics and cell genetics},
  year={1986},
  volume={42 1-2},
  pages={1-7}
}
Polyspermy occurs with a frequency of about 12% under some hormonal regimens currently being used for in vitro fertilization and embryo transfer. Oocytes with three pronuclei usually show normal cleavage and are morphologically indistinguishable from embryos produced by normal fertilization. Chromosome studies and DNA measurements on dispermic embryos show that about one-half are triploid, the others having either a normal diploid chromosome complement or a severely depleted chromosome… CONTINUE READING