Consequences of peripheral chemoreflex inhibition with low-dose dopamine in humans.

@article{Niewiski2014ConsequencesOP,
  title={Consequences of peripheral chemoreflex inhibition with low-dose dopamine in humans.},
  author={Piotr Niewiński and Stanisław Tubek and Waldemar Banasiak and Julian Paton and Piotr P Ponikowski},
  journal={The Journal of physiology},
  year={2014},
  volume={592 6},
  pages={1295-308}
}
Low-dose dopamine inhibits peripheral chemoreceptors and attenuates the hypoxic ventilatory response (HVR) in humans. However, it is unknown: (1) whether it also modulates the haemodynamic reactions to acute hypoxia, (2) whether it also modulates cardiac baroreflex sensitivity (BRS) and (3) if there is any effect of dopamine withdrawal. We performed a double-blind, placebo-controlled study on 11 healthy male volunteers. At sea level over 2 days every subject was administered low-dose dopamine… CONTINUE READING

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