Consequences of perinatal bisphenol A exposure in a mouse model of multiple sclerosis.

@article{BrinkmeyerLangford2014ConsequencesOP,
  title={Consequences of perinatal bisphenol A exposure in a mouse model of multiple sclerosis.},
  author={Candice L Brinkmeyer-Langford and Aline Andr{\'e} Rodrigues and Kelli J Kochan and Rachel M Haney and Fenan S Rassu and Andrew J. Steelman and Colin Young and Penny K Riggs and Ralph W Storts and Mary W. Meagher and C. Jane Welsh},
  journal={Autoimmunity},
  year={2014},
  volume={47 1},
  pages={57-66}
}
Multiple sclerosis (MS) is a complex disease influenced by genetic and environmental contributing factors. Endocrine disrupting compounds (EDCs) such as bisphenol A (BPA) affect gene expression and hormone-regulated systems throughout the body. We investigated the effects of BPA on Theiler's-virus induced demyelination (TVID), a mouse model of MS. Perinatal BPA exposure, combined with viral infection, resulted in a decreased level of viral antibodies, accelerated the onset of TVID symptoms… CONTINUE READING

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